i4C-6/7 R&D Models

Resources invested globally in the field of global health Research & Development (R&D) for biomedical innovations such as drugs, vaccines and diagnostics to tackle diseases have been limited and in many neglected disease areas are now stagnant. Investments in global health R&D are instrumental for accelerating and sustaining global health R&D pipelines. With adequate funding and a systematic prioritization, global health R&D has the potential to deliver appropriate R&D products targeting low and middle income country populations, contributing to the alleviation of morbidity and socioeconomic burden among the world’s poor. In the absence of systematic priority setting, there is a risk of misallocation of valuable, yet scarce, resources in global health R&D.


i4C-6 and i4C-7 projects aim to review current approaches to pharmaceutical R&D priority setting and their relevance to global health R&D as well as critically examine how they relate and differ, how they can complement each other, and how their usefulness varies across contextual factors and stages in the global health R&D funding flow chain. Against this review, the projects aim to develop and to test new methodologies
for the systematic prioritization of global health R&D investments, by applying multi-criteria decision analysis and combinatorial optimization techniques. The projects aim to ultimately assess whether a ‘multi-criteria value-maximization’ tool can be applied for the prioritization of investments in global health R&D, recognizing the existence of multiple objectives and variable preferences between organizations responsible for funding, managing and conducting R&D across different sectors, national income and geographical clusters.

i4C-6/7 Project Team

Dimitrios Gouglas

Dimitrios Gouglas

i4C PhD Candidate, Global Strategy Lab
and University of Oslo
Adviser, Norwegian Institute of Public Health
Trygve Ottersen

Trygve Ottersen

Faculty Associate, Global Strategy Lab
Adjunct Professor of Law, University of Ottawa
Associate Professor of Medicine, University of Oslo